2023
Hendren C, Li WP, Stegemann JP, Hall TL, Deng CX. Multichannel resonant acoustic rheometry system for quantification of coagulation of multiple human plasma samples. Scientific Reports. Nov 2023. https://doi.org/10.1038/s41598-023-46518-w.
Xu Z, Liu SY, Xue X, Li WP, Fu JP, Deng CX. Rapid responses of human pluripotent stem cells to cyclic mechanical strains applied to integrin by acoustic tweezing cytometry. Scientific Reports. Oct 2023. https://doi.org/10.1038/s41598-023-45397-5.
2022
Li WP, Hobson EC, Bunch CM, Miller JB, Nehme J, Kwaan HC, Walsh MM, McCurdy MT, Aversa JG, Thomas AV, Zackariya N, Thomas SJ, Smith SA, Cook BC, Boyd B, Stegemann JP, Deng CX. Resonant Acoustic Rheometry to Measure Coagulation Kinetics in Hemophilia A and Healthy Plasma: A Novel Viscoelastic Method. Semin Thromb Hemost. Nov 2022. doi: 10.1055/s-0042-1757896.
2021
Hobson EC, Li WP, Juliar BA, Putnam AJ, Stegemann JP, Deng CX. Resonant acoustic rheometry for non-contact characterization of viscoelastic biomaterials. Biomaterials. Feb 2021. 10.1016/j.biomaterials.2021.120676
Edwards NJ, Hobson E, Dey D, Rhodes A, Overmann A, Hoyt B, Walsh SA, Pagani CA, Strong AL, Hespe GE, Padmanabhan KR, Huber A, Deng CX, Davis TA, Levi B. High Frequency Spectral Ultrasound Imaging Detects Early Heterotopic Ossification in Rodents. Stem Cells and Development. May 2021. https://doi.org/10.1089/scd.2021.0011
2020
Fan Z, Xue X, Fu JP, Deng CX. Visualization and quantification of dynamic intercellular coupling in human embryonic stem cells using single cell sonoporation. Scientific Reports. Oct 2020. 10.1038/s41598-020-75347-4
Friend NE, Rioja AY, Kong YP, Beamish JA, Hong XW, Habif JC, Bezenah JR, Deng CX, Stegemann JP, Putnam AJ. Injectable pre-cultured tissue modules catalyze the formation of extensive functional microvasculature in vivo. Sep 2020. 10.1038/s41598-020-72576-5
2019
Bushnell GG, Hong X, Hartfield RM, Zhang Y, Oakes RS, Rao SS, Jeruss JS, Stegemann JP, Deng CX, Shea LD. High frequency spectral ultrasound imaging to detect metastasis in implanted biomaterial scaffolds. Ann Biomed Eng. 2019 Sep 23. doi: 10.1007/s10439-019-02366-2.
Topal T, Fan Z, Deng L, Krebsbach PH, Deng CX. Integrin-targeted Cyclic Forces Accelerate Neural Tube-like Rosette Formation from Human Embryonic Stem Cells. Advanced Biosystems. 2019, 1900064. DOI: 10.1002/adbi.201900064
Hong X, Rzeczycki PM, Keswani RK, Murashov MD, Fan Z, Deng CX, Rosania GR. Acoustic tweezing cytometry for mechanical phenotyping of macrophages and mechanopharmaceutical cytotripsy. Scientific Reports. 2019. Apr 5;9(1):5702. DOI: 10.1038/s41598-019-42180-3. PMID: 30952950; PMCID: PMC6450871.
Topal T, Kim B, Villa-Diaz L, Deng CX, Takayama S, Krebsbach PH. Rapid translocation of pluripotency-related transcription factors by external uniaxial forces. Integrative Biology. 2019. doi: 10.1093/intbio/zyz003. PMID: 30809641
2018
Fan Z, Xu X, Perera R, Esfahani SN, Exner AA, Fu J, Deng CX. Acoustic actuation of integrin-bound microbubbles for mechanical phenotyping during differentiation and morphogenesis of human embryonic stem cells. Small. 2018. 14(50):1803137. https://doi.org/10.1002/smll.201803137. PMID: 30427572
Topal T, Hong X, Xue X, Fan, Z, Kanetkar N, Nguyen JT, Fu J, Deng CX, and Krebsbach PH. Acoustic Tweezing Cytometry Induces Rapid Initiation of Human Embryonic Stem Cell Differentiation. Scientific Reports. 2018; 8:12977 | DOI:10.1038/s41598-018-30939. PMID: 30154528; PMCID: PMC6113316
Hong X, Annamalai RT, Kemerer T, Deng CX, Stegemann JP. Multimode Ultrasound Viscoelastography for Three-Dimensional Interrogation of Microscale Mechanical Properties in Heterogeneous Biomaterials. Biomaterials. 2018; 178:11-22. doi: 10.1016/j.biomaterials.2018.05.057. PMID 29902533
Ranganathan K*, Hong X*, Cholok D, Habbouche J, Priest C, Breuler C, Chung M, Li J, Kaura A, Hsieh HHS, Butts J, Ucer S, Schwartz E, Buchman SR, Stegemann JP, Deng CX, Levi B. High-frequency spectral ultrasound imaging (SUSI) visualizes early post-traumatic heterotopic ossification (HO) in a mouse model. Bone. 2018; 109:49-55. doi: 10.1016/j.bone.2018.01.034. PMID: 29412179
2017
Xue X, Hong X, Li Z, Deng CX, Fu J. Acoustic tweezing cytometry enhances osteogenesis of human mesenchymal stem cells through cytoskeletal contractility and YAP activation. Biomaterials. 2017; 134:22-30. PMID: 28453955; PMCID: PMC5506541
2016
Kubanek J, Shi J, Marsh J, Chen D, Deng CX, Cui J. Ultrasound modulates an ion channel current. Scientific Reports 2016; 6: 24170. doi:10.1038/srep24170
Hong X, Stegemann J, Deng CX. Microscale Characterization of the Viscoelastic Properties of Hydrogel Biomaterials using Ultrasound Technique. Biomaterials 2016; 88:12-24, 2016. doi: 10.1016/j.biomaterials.2016.02.019. PMCID: PMC4964754
Deng CX, Hong X, Stegemann. Ultrasound imaging techniques for spatiotemporal characterization of composition, microstructure, and mechanical properties in tissue engineering. Tissue Engineering B 2016; 22: 311-321. PMID: 26771992
Hsiao Y, Deng CX. Calibration and evaluation of ultrasound thermography using infrared imaging. Ultrasound Med Biol. 2016; 42: 503-517. PMID: 26547634
Xu G, Meng Z, Lin J, Deng CX, Carson P, Fowlkes JB, Tao C, Liu X, Wang X. High resolution Physio-chemical Tissue Analysis: Towards Non-invasive In Vivo Biopsy. Scientific Reports. 2016; 6: 16937. doi:10.1038/srep16937
2015
Feng T, Perosky JE, Kozloff KM, Xu G, Cheng Q, Du S, Yuan J, Deng CX, Wang X. Characterization of bone microstructure using photoacoustic spectrum analysis. Optical Express. 2015; 23 (19): 25217-25224.
Feng T, Kozloff KM, Tian C, Perosky JE, Hsiao Y, Du S, Yuan J, Deng CX, Wang X. Bone assessment via thermal photo-acoustic measurements. Opt. Lett. 2015; 40: 1721-1724.
Chen D, Sun Y, Deng CX, Fu J. Improving survival of disassociated human embryonic stem cells by mechanical stimulation using acoustic tweezing cytometry. Biophysical Journal. 2015; 108 (3): 1315-1317. PMC 4375556
Chen D, Sun Y, Gudur MSR, Hsiao Y, Wu Z, Fu J, Deng CX. Two bubble acoustic tweezing cytometry for biomechanical probing and stimulation of cells. Biophysical Journal. 2015;108(1):32-42. PMCID: PMC4286600
Wu Z, Kumon RE, Laughner JI. Efimov IR, Deng CX. Characteristics and Correlation of Electrophysiological Changes with Temperature Increases Induced by High-Intensity Focused Ultrasound Ablation. Ultrasound Med Biol 2015; 41: 432-448.
2014
Heureaux J, Chen D, Murray VL, Deng CX, Liu AP. Activation of a bacterial mechanosensitive channel in mammalian cells by cytoskeletal stress. Cellular and Molecular Bioengineering. 2014; 7(3): 307-319. PMID: 25606062; PMCID: PMC4297646 DOI: 10.1007/s12195-014-0337-8
Rao R, Ceccarelli J, Vigen ML, Gudur M, Singh R, Deng CX, Putnam AJ, Stegemann JP. Effects of Hydroxyapatite on Endothelial Network Formation in Collagen/Fibrin Composite Hydrogels In Vitro and In Vivo. Acta Biomaterialia. 2014; 10(7):3091-3097.
Fan Z, Kumon RE, Deng CX. Mechanisms of microbubble-facilitated sonoporation
for drug and gene delivery. Therapeutic delivery. 2014; 5(4): 467-486.
Fan Z, Chen D, Deng CX. Dynamic activities of a population of microbubbles driven by pulsed ultrasound exposures in sonoporation. Ultrasound Med Biol. 2014; 40(6):1260-72.
Gudur MSR, Rao RR, Hsiao Y, Peterson AW, Stegemann JP, Deng CX. Noninvasive Quantification of In Vitro Osteoblastic Differentiation in 3D Engineered Tissue Constructs using Spectral Ultrasound Imaging. Plos One 2014; Jan 22;9(1):e85749. doi: 10.1371/journal.pone.0085749.
2013
Wu Z, Gudur MS, Deng CX. Transmural Ultrasound Imaging of Thermal Lesion and Action Potential Changes in Perfused Canine Cardiac Wedge Preparations by High Intensity Focused Ultrasound Ablation. Plos One. 8(12): e82689. Dec 12, 2013.
Fan Z, Chen D, Deng CX. Improving ultrasound gene transfection efficiency by controlling ultrasound excitation of microbubbles. J Control Release. 2013 Sep 28;170(3):401-13.
Hsiao YS, Kumon RE, Deng CX. Characterization of Lesion Formation and Bubble Activities during High Intensity Focused Ultrasound Ablation using Temperature-Derived Parameters. Infrared Phys Technol. 2013 Sep 1;60:108-117.
Yin L, Gudur MS, Hsiao YS, Kumon RE, Deng CX, Jiang H. Tomographic Reconstruction of Tissue Properties and Temperature Increase for High-Intensity Focused Ultrasound Applications. Ultrasound Med Biol. 2013 Jul 9.
Fan Z*, Sun Y*, Chen D*, Tay D, Chen W, Deng CX, Fu J. Acoustic tweezing cytometry for live-cell subcellular modulation of intracellular cytoskeleton contractility. Scientific Reports. 2013 Jul 12;3:2176.(*Contribute equally)
Frampton JP*, Fan Z*, Simon A*, Chen D, Deng CX, Takayama S. Aqueous two-phase system patterning of microbubbles for localized sonoporation of cells. Advanced Functional Materials. 2013 Jul 23;27:3366.(*Contribute equally)
Hsiao YS, Wang X, Deng CX. Dual-wavelength photoacoustic technique for monitoring tissue status during thermal treatments. J Biomed Opt. 2013 Jun;18(6):067003.
2012
Xu G, Dar IA, Tao C, Liu X, Deng CX, Wang X. Photoacoustic spectrum analysis for microstructure characterization in biological tissue: A feasibility study. Appl Phys Lett. 2012 Nov 26;101(22):221102.
Fan Z, Liu H, Mayer M, Deng CX. Spatiotemporally controlled single cell sonoporation. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16486-91.
Gudur MS, Kumon RE, Zhou Y, Deng CX. High-frequency rapid B-mode ultrasound imaging for real-time monitoring of lesion formation and gas body activity during high-intensity focused ultrasound ablation. IEEE Trans Ultrason Ferroelectr Freq Control. 2012 Aug;59(8):1687-99.
Gudur MS, Rao RR, Hsiao YS, Peterson AW, Deng CX, Stegemann JP. Noninvasive, quantitative, spatiotemporal characterization of mineralization in three-dimensional collagen hydrogels using high-resolution spectral ultrasound imaging. Tissue Eng Part C Methods. 2012 Dec;18(12):935-46.
Kumon RE, Repaka A, Atkinson M, Faulx AL, Wong RC, Isenberg GA, Hsiao YS, Gudur MS, Deng CX, Chak A. Characterization of the pancreas in vivo using EUS spectrum analysis with electronic array echoendoscopes. Gastrointest Endosc. 2012 Jun;75(6):1175-83.
Fang Y, Frampton JP, Raghavan S, Sabahi-Kaviani R, Luker G, Deng CX, Takayama S. Rapid generation of multiplexed cell cocultures using acoustic droplet ejection followed by aqueous two-phase exclusion patterning. Tissue Eng Part C Methods. 2012 Sep;18(9):647-57.
Kumon RE, Repaka A, Atkinson M, Faulx AL, Wong RC, Isenberg GA, Hsiao YS, Gudur MS, Deng CX, Chak A. Lymph node characterization in vivo using endoscopic ultrasound spectrum analysis with electronic array echo endoscopes. Endoscopy. 2012 Jun;44(6):618-21.
Kumon RE, Gudur MS, Zhou Y, Deng CX. High-frequency ultrasound m-mode imaging for identifying lesion and bubble activity during high-intensity focused ultrasound ablation. Ultrasound Med Biol. 2012 Apr;38(4):626-41.
Laughner JI, Sulkin MS, Wu Z, Deng CX, Efimov IR. Three potential mechanisms for failure of high intensity focused ultrasound ablation in cardiac tissue. Circ Arrhythm Electrophysiol. 2012 Apr;5(2):409-16.
Zhou Y, Yang K, Cui J, Ye JY, Deng CX. Controlled permeation of cell membrane by single bubble acoustic cavitation. J Control Release. 2012 Jan 10;157(1):103-11.
2011
Kumon RE, Deng CX, Wang X. Frequency-domain analysis of photoacoustic imaging data from prostate adenocarcinoma tumors in a murine model. Ultrasound in Medicine and Biology 2011. 37:834-839.
Park J, Fan Z, Deng CX. Effects of shear stress cultivation on cell membrane disruption and intracellular calcium concentration in sonoporation of endothelial cells. Journal of Biomechanics 2011. 44:164-169.
Chow CM, Zhou Y, Guo Y, Norris TB, Wang X, Deng CX, Ye JY. Broadband optical ultrasound sensor with a unique open-cavity structure. J Biomed Opt. 2011 Jan-Feb;16(1):017001.
Deng CX, Huang X. Improved outcome of targeted delivery of chemotherapy drugs to the brain using a combined strategy of ultrasound, magnetic targeting and drug-loaded nanoparticles. Ther Deliv. 2011 Feb;2(2):137-41.
2010
Deng CX. Targeted drug delivery across the blood-brain barrier using ultrasound technique. Ther Deliv. 2010 Dec;1(6):819-48.
Grainger SJ, Serna JV, Sunny S, Zhou Y, Deng CX, El-Sayed MEH. Pulsed ultrasound enhances nanoparticle penetration into breast cancer spheroids. Molecular Pharmaceutics 2010; 7:2006-2019.
Zhang JF, Villacorta L, Chang L, Fan ZZ, Hamblin M, Zhu TQ, Chen CS, Cole MP, Schopfer FJ, Deng CX, Garcia-Barrio MT, Feng YH, Freeman BA, Chen YE. Nitro-oleic acid inhibits angiotensin II-induced hypertension. Circulation Research 2010. 107: 540-U200.
Park J, Fan Z, Kumon RE, El-Sayed ME, Deng CX. Modulation of intracellular calcium concentration in brain microvascular endothelia cells in vitro by acoustic cavitation. Ultrasound in Medicine and Biology 2010; 36:1176-1187.
Fan Z, Kumon RE, Park J, Deng CX. Intracellular delivery and calcium transients generated in sonoporation facilitated by microbubbles. Journal of Controlled Release 2010; 142:31-39.
Kumon RE, Pollack MJ, Faulx AL, Olowe K, Farooq FT, Chen VK, Zhou Y, Wong RCK, Isenberg GA, Sivak MV, Chak A, Deng CX. In vivo characterization of pancreatic and lymph node tissue using endoscopic ultrasound spectrum analysis: Validation study. Gastrointestinal Endoscopy 2010; 71:53-63.
Deng CX, Exner A. Image-guided therapeutics. Mol Pharm. 2010 Feb 1;7(1):1-2.
2009
Jia C, Olafsson R, Kim K, Kolias TJ, Rubin JM, Weitzel WF, Witte RS, Huang SW, Richards MS, Deng CX, O’Donnell M. Two-dimensional strain imaging of controlled rabbit hearts. Ultrasound in Med Biol 2009; 35:1488-1501.
Zhou Y, Kumon RE, Cui J, Deng CX. The size of sonoporation pores on the cell membrane. Ultrasound in Medicine and Biology 2009; 35:1756-1760.
Yang K, Zhou Y, Ren Q, Ye J, Deng CX. Dynamics of microbubble generation and trapping by self-focused femtosecond laser pulses. Applied Physics Letters 2009; 95: 051107. doi:10.1063/1.3187535
Kumon RE, Aehle M, Sabens D, Parikh P, Han YW, Kourennyi D, Deng CX. Spatiotemporal effects of sonoporation on mammalian cells measured by real-time calcium imaging. Ultrasound in Med and Biol 2009; 35: 494-506.
Kumon RE, Pollack MJ, Faulx AL, Olowe K, Farooq FT, Chen VK, Zhou Y, Wong RC, Isenberg GA, Sivak MV, Chak A, Deng CX. Characterization of pancreatic cancer and intra-abdominal lymph node malignancy using spectrum analysis of endoscopic ultrasound imaging. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:1949-52.
2008
Zhou Y, Cui J, Deng CX. Dynamics of sonoporation correlated with acoustic cavitation activities. Biophysical J. 2008; 94(7):L51-3.
Zhou Y, Shi J, Cui J, Deng CX. Effects of extracellular calcium on cell membrane resealing in sonoporation. Journal of Controlled Release 2008; 126 (1):34-43.
Chen V, Marks J, Wong R, McGee M, Faulx A, Isenberg G, Schomisc S, Deng CX, Ponsky J, Chak A. Creation of an effective and reproducible nonsurvival porcine model that simulates actively bleeding peptic ulcers. Gastrointestinal Endoscopy 2008; 68(3):548-53.
O’Brien Jr WD, Deng CX, Harris GR, Herman BA, Merritt CR, Sanghvi N, Zachary JF. The risk of exposure to diagnostic ultrasound in postnatal subjects: thermal effects. J Ultrasound Med. 2008; 27(4):517-35.
Fowlkes JB, Abramowicz JS, Church CC, Holland CK, Miller DL, O’Brien Jr. WD, Sanghvi NT, Stratmeyer ME, Zachary JF, Deng CX, Harris GR, Herman BA, Hynynen KH, Merritt CRB, Thomenius KE, Bailey MR, Carson PL, Carstensen EL, Frizzell LA, Nyborg WL, Barnett SB, Duck FA, Edmonds PD, Ziskin MC, Abbott JG, Dalecki D, Dunn F, Greenleaf JF, Salvesen KA, Siddiqi TA, Averkiou MA, Brayman AA, Everbach EC, Wible Jr. JH, Wu J, Simpson DG. American Institute of Ultrasound in Medicine consensus report on potential bioeffects of diagnostic ultrasound: Executive summary. Journal of Ultrasound in Medicine 2008; 27 (4): 503-515.
2007
Kumon RE, Olowe K, Farooq FT, Chen V, Zhou Y, Faulx A, Iseenberg GA, Sivak MV, Chak A, Deng CX. Endoscopic ultrasound spectrum analysis for in vivo tissue characterization in the pancreas and intra-abdominal and mediastinal lymph nodes: A pilot study. Gastrointestinal Endoscopy 2007; 66(6): 1096-1106.
Kumon RE, Aehle M, Sabens D, Parikh P, Kourennyi D, Deng CX. Ultrasound-induced calcium oscillations and waves in chinese hamster ovary cells in the presence of microbubbles. Biophysical Journal 2007; 93 (6): L29-31.
Han Y, Ikegami A, Chung P, Zhang L, Deng CX. Sonoporation is an efficient tool for intracellular fluorescent dextran delivery and one-step double-crossover mutant construction in Fusobacterium nucleatum. Applied and Environmental Microbiology 2007; 73: 3677-3683.
2006 & before
Frenkel V, Oberoi J, Stone MJ, Park M, Deng CX, Wood BJ, Neeman Z, Horne H III, Li K. Pulsed-high intensity focused ultrasound (HIFU) enhances thrombolysis in an in vitro model. Radiology 2006; 239:86-93.
Han Y, Ikegami A, Rajanna C, Kawsar H, Zhou Y, Li M, Sojar HT, Genco RJ, Kuramitsu HK, Deng CX. Identification and characterization of a novel adhesin unique to oral fusobacteria. Journal of Bacteriology 2005; 187(15): 5330-5340.
Deng CX, Qu F, Nikolski VP, Zhou Y, Efimov IR. Fluorescent real-time monitoring of cardiac focal ablation with HIFU in vitro. Annals of Biomedical Engineering. 2005; 33: 1417-1424.
Pan H, Zhou Y, Izadnegahdar O, Cui J, Deng CX. Study of sonoporation dynamics affected by ultrasound duty cycle. Ultrasound Med Biol 2005; 31: 849-56.
Deng CX, Sieling F, Pan H, Cui J. Ultrasound induced cell-membrane porosity. Ultrasound Med Biol 2004; 30:519-526.
Deng CX, Dogra V, Exner A, Wang H, Bhatt S, Zhou Y, Stowe NT, Haaga JR. A feasibility study of high intensity focused ultrasound for liver biopsy hemostasis. Ultrasound Med Biol 2004; 30:1531-1537.
Lizzi FL, Feleppa EJ, Alam SK, Deng CX. Ultrasonic spectrum analysis for tissue evaluation. Special Issue on Ultrasonic Image Processing & Analysis in Pattern Recognition Letters 2003; 24: 637-658.
Lizzi FL, Muratore R, Deng CX, Ketterling JA, Alam SK, Mikaelian S, Kalisz A. Radiation-force technique to monitor lesions during ultrasonic therapy. Ultrasound Med Biol 2003; 29:1593-160.
Deng CX, Lizzi FL. A review of physical phenomena associated with ultrasonic contrast agents and illustrative clinic applications. Ultrasound Med Biol 2002; 28: 277-286.
Feleppa E, Alam SK, Deng CX. Emerging ultrasound technologies for imaging early markers of disease. J Disease Marker 2002; 18:249-268.
Silverman RH, Lizzi FL, Ursea BG, Cozzarelli L, Ketterling JA, Deng CX, Folberg R, Coleman DJ. Safety levels for exposure of cornea and lens to very high-frequency ultrasound. J Ultrasound Med 2001; 20: 979-986.
Deng CX, Lizzi FL, Rosado A, Silverman RH, Coleman DJ. Study of contrast agents using a dual-frequency-band technique. Ultrasound Med Biol 2000; 26: 819-831.
Lizzi FL, Deng CX, Lee P, Rosado A, Silverman RH, Coleman DJ. A comparison of ultrasonic beams for thermal treatment of ocular tumors. Eur J Ultras 1999; 9:71-78.
Deng CX, Lizzi FL, Silverman RH, Ursea R, Coleman DJ. Imaging and spectrum analysis of contrast agents in the in vivo rabbit eye using very high frequency ultrasound. Ultrasound Med Biol 1998; 24(3): 383-394.
Lizzi FL, Astor M, Liu T, Deng CX, Coleman DJ, Silverman RH. Ultrasonic spectrum analysis for tissue assays and therapy evaluation. Int. J. Imag. Sys. Tech. 1997; 8:3-10.
Deng CX, Xu Q, Apfel RE, Holland CK. In vitro measurements of inertial cavitation thresholds in human blood. Ultrasound Med Biol. 1996;22(7):939-48.
Holland CK, Deng CX, Apfel RE, Alderman JL, Fernandez LA, Taylor KJ. Direct evidence of cavitation in vivo from diagnostic ultrasound. Ultrasound Med Biol. 1996;22(7):917-25.
Deng CX, Xu Q, Apfel RE, Holland CK. Inertial cavitation produced by pulsed ultrasound in controlled host media. J Acoust Soc Am. 1996 Aug;100(2 Pt 1):1199-208.
Zheng X, Apfel RE. Acoustic interaction forces between two fluid spheres in an acoustic field. J. Acoust. Soc. Am. 1995; 97: 2218-2226. (*maiden name X. Zheng used.)
Wei R, Wang B, Mao Y, Zheng X, Miao G. Further investigation of nonpropagating solitons and their transition to chaos. J. Acoust. Soc. Am. 1990; 88: 469-472. (*maiden name X. Zheng used.)