The ultimate goal of our research is to develop new and improved strategies utilizing ultrasound technologies for the diagnosis and treatment of human diseases. Our research focus is to increase the mechanistic understanding of ultrasound interaction with biological systems (from tissue to cells) and to employ the ensuing insight to develop new technologies. Research projects funded by the U.S. National Institutes of Health (NIH) and other agencies include ultrasound mediated cell membrane poration (sonoporation) for non-viral drug and gene delivery, quantitative ultrasound imaging and techniques for tissue engineering, and novel ultrasound techniques (acoustic tweezing) for mechanobiology applications. Our work has been published in a variety of professional journals including PNAS, Small, Biomaterials, Tissue Engineering, Scientific Reports, Ultrasound in Medicine and Biology, Radiology, Annals of Biomedical Engineering, Journal of Controlled Release, Journal of Bacteriology, Biophysical Journal, Gastrointestinal Endoscopy, Applied and Environmental Microbiology, Applied Physics Letter, and Journal of the Acoustical Society of America.
Cheri Deng, Ph.D.
Professor of Biomedical Engineering